Clinical significance of nasopharyngeal bacterial colonization in children with acute bronchiolitis
10.3760/cma.j.issn.1671-7368.2013.09.010
- VernacularTitle:毛细支气管炎患儿鼻咽部定植菌临床意义探讨
- Author:
Zhengrong CHEN
;
Yuqing WANG
;
Yongdong YAN
;
Canhong ZHU
;
Li HUANG
;
Meijuan WANG
;
Wei JI
- Publication Type:Journal Article
- Keywords:
Bronchiolitis;
Respiratory syncytial virus;
Child,preschool
- From:
Chinese Journal of General Practitioners
2013;12(9):722-725
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To explore the effects of nasopharyngeal bacterial colonization in children with acute bronchiolitis due to respiratory syncytial virus (RSV).Methods Hospitalized children of acute bronchiolitis were enrolled to detect pathogen and bacterial colonization.Their clinical data and laboratory results were collected and analyzed.Cases of elective surgery were also obtained as control group.Results Fifty-five percent of all children with bronchiolitis had a lower positive rate of nasopharyngeal bacterial culture (55.0％ vs.74.1％,P ＜0.01).Children with nasopharyngeal bacterial colonization had a higher rate of severe bronchiolitis (13.8％ vs.4.2％,P =0.018),presented dyspnea more frequently (19.8％ vs.9.5％,P =0.037) and had a longer hospital duration (8.2 vs.7.5 days,P =0.036) as compared with those without bacterial colonization.In terms of laboratory results,a higher proportion of C-reactive protein was found in children with bacterial colonization than those with non-bacterial colonizations (17.2％ vs.4.2％,P =0.003).Conclusion Bacterial colonization may be a predictor for severe bronchiolitis.
