Risk factors for recurrence after radical resection of node-negative advanced gastric cancer
10.3760/cma.j.issn.1007-631X.2013.10.002
- VernacularTitle:淋巴结转移阴性进展期胃癌术后复发危险因素分析
- Author:
Xuguang JIAO
;
Han LIANG
;
Jingyu DENG
;
Li WANG
;
Honggen LIU
;
Yuexiang LIANG
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Neoplasm recurrence,local;
Neoplasm metastasis;
Risk factors
- From:
Chinese Journal of General Surgery
2013;28(10):732-735
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the risk factors for recurrence of node-negative advanced gastric cancer(N0-AGC) after radical resection.Methods Data of 270 N0-AGC cases after curative intent resection were collected from 2001 to 2008 in Tianjin Cancer Hospital.There were 45 cases with postoperative recurrence.Univariate and multivariate analysis were applied to investigate risk factors for postoperative recurrence.Results The recurrence time was 2-68 months,the survival time was 5-87 months.Univariate analysis showed that tumor size,depth of tumor invasion,number of negative lymph nodes were associated with recurrence of N0-AGC.Multivariate analysis identified tumor size,depth of tumor invasion,number of negative lymph nodes as independent recurrence factors for entire cohort,depth of tumor invasion,number of negative lymph nodes were risk factors for locoregional recurrence.Tumor size,adjuvant chemotherapy for hematogenous metastasis.Conclusions For T4 stage,tumor diameter ＞4 cm advanced node-negative gastric cancer patients,extended lymphadenectomy was recommended to decrease locoregional recurrence,and adjuvant chemotherapy to reduce hematogenous spread.
