Roles of CD4+ T lymphocytes in hepatocellular carcinoma
10.3760/cma.j.issn.1673-422X.2013.10.020
- VernacularTitle:CD4+T细胞在肝细胞癌中的作用
- Author:
Xiuhua XU
;
Xiaoxing XIANG
- Publication Type:Journal Article
- Keywords:
Carcinoma,hepatocellular;
Immunity;
CD4 + T lymphocytes
- From:
Journal of International Oncology
2013;40(10):785-788
- CountryChina
- Language:Chinese
-
Abstract:
As a series of multifunctional cells,recent studies indicate that most of the CD4 + T lymphocyte subsets involve in the tumor angiogenesis and invasion,the apoptosis of tumor cells,and the expressions of acute phase proteins and cancer-promoting genes by activating or inhibiting the innate immune cells,the adaptive immune cells and non-immune cells,thus function as tumor promoters or inhibitors in hepatocellular carcinoma (HCC).