Research progress in novel biomarkers of acute kidney injury after cardiac surgery
10.3760/cma.j.issn.1673-4203.2013.10.010
- VernacularTitle:急性肾损伤生物学标志物在心脏外科术后的研究进展
- Author:
Yinying XUE
;
Yongsheng NIU
;
Xinwei MU
- Publication Type:Journal Article
- Keywords:
Acute kidney injury;
Biomarkers;
Neutrophil gelatinase-associated lipocalin;
Interleukin-18;
Kidney injury molecule-1;
Postoperative complications;
Cardiac surgical procedures
- From:
International Journal of Surgery
2013;40(10):677-680
- CountryChina
- Language:Chinese
-
Abstract:
Acute kidney injury (AKI) is a common and serious clinical syndrome after cardiac surgery with the high morbidity and mortality.As the markers of AKI,Serum creatinine and urine output is not sensitive for early detection.Due to the lack of early biomakers for AKI,early effective treatment has been delayed.Identification of novel biomarkers for AKI has progressed to the clinical phase.Novel biomakers include neutrophil gelatinase-associated lipocalin,kidney injury molecule-1,Cystatin C,IL-18,and so on.In this article the author will review the current progress of these clinical and experimental novel AKI biomarkers.
