PPARγ and the invasion and metastasis of hepatocellular carcinoma
10.3760/cma.j.issn.1673-422X.2013.10.019
- VernacularTitle:PPARγ与肝细胞癌的侵袭和转移
- Author:
Chuang WANG
;
Ping XUE
;
Liangqi CAO
- Publication Type:Journal Article
- Keywords:
Peroxisome proliferator-activated receptors;
Liver neoplasms;
Neoplasm metastasis
- From:
Journal of International Oncology
2013;40(10):782-784
- CountryChina
- Language:Chinese
-
Abstract:
Recent studies indicate that the activation of peroxisome proliferator-activated receptor gamma (PPARγ) can inhibit the invasion and metastasis of hepatocellular carcinoma (HCC) by inhibiting proliferation and adhesion of HCC cells,degradation of extracellular matrix and angiogenesis.Therefore,the mechanisms that PPARγsignaling pathway inhibits the invasion and metastasis of HCC may provide help for the clinical treatment,and is expected to improve the survival rate of HCC patient.
