Roles of miR-494 in tumors
10.3760/cma.j.issn.1673-422X.2013.10.002
- VernacularTitle:微小RNA-494在肿瘤发生发展中的作用
- Author:
Mingchun LI
;
Aibing WU
;
Zhixiong YANG
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Neoplasms;
Target gene
- From:
Journal of International Oncology
2013;40(10):726-729
- CountryChina
- Language:Chinese
-
Abstract:
MiR-494 involves in cell cycle regulation,differentiation and apoptosis processes of normal ceils.Recent study shows that abnormal expression of miR-494 is associated with oncogenesis closely,and it participates in the invasion and metastasis of tumor cells and so on.MiR-494 is not only a tumor suppressor gene,but also can be considered as a cancer-promoting gene.MiR-494 can regulate the oncogenesis and development of the tumor through a variety of target genes and signaling pathways.
