Wnt/β-catenin signaling pathway and glioma
10.3760/cma.j.issn.1673-422X.2013.09.009
- VernacularTitle:Wnt/β-catenin信号转导通路与脑胶质瘤
- Author:
Mengna CHEN
;
Ting LIU
;
Geng GUO
- Publication Type:Journal Article
- Keywords:
Glioma;
Cell proliferation;
Neoplasm invasiveness;
Apoptosis;
Wnt/β-catenin signaling pathway
- From:
Journal of International Oncology
2013;40(9):668-670
- CountryChina
- Language:Chinese
-
Abstract:
Wnt/β-catenin signaling pathway is highly conserved in evolution,which involves in the regulation of a variety of biological processes such as embryonic growth,development,energy metabolism and stem cells maintenance.Aberrant activation of Wnt/β-catenin signaling pathway has a closely relationship with tumorigenesis.Investigating the role of Wnt/β-catenin signaling in glioma cell proliferation,invasion,apoptosis and tumor angiogenesis will provide novel therapeutic targets and intervening measures for glioma treatment.
