Apolipoprotein E gene polymorphism and ischemic stroke
10.3760/cma.j.issn.1673-4165.2013.09.006
- VernacularTitle:载脂蛋白E基因多态性与缺血性卒中
- Author:
Yun YANG
;
Hong XU
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain Ischemia;
Apolipoproteins E;
Polymorphism,Genetic
- From:
International Journal of Cerebrovascular Diseases
2013;21(9):693-696
- CountryChina
- Language:Chinese
-
Abstract:
Apolipoprotein E (ApoE) has gene polymorphism (ε2,ε3,and ε4).It has been confirmed that ApoE structural and functional abnormlities are closely associated with the hyperlipidemia,formation of atherosclerosis,and its severity,while both hyperlipidemia and atherosclerosis are the risk factors for ischemic stroke.In recent years,although the relationship between the ApoE gene polymorphism and ischemic stroke has been extensively studied,the conclusions are not consistent.This article reviews the correlation studies between the ApoE gene polymorphism and ischernic stroke.
