A clinical study on cerebral edema of intra-arterial thrombolytic recanalization in acute ischemic stroke
10.3969/j.issn.1671-8348.2013.28.010
- VernacularTitle:急性脑梗死动脉溶栓血管再通后的脑水肿研究
- Author:
Hai MA
;
Yajing REN
;
Xiduo ZHANG
;
Jing LIU
;
Fengli HAO
- Publication Type:Journal Article
- Keywords:
brain infarction;
intra-arterial thrombolysis;
brain edema;
head;
tomography,X-ray computed
- From:
Chongqing Medicine
2013;(28):3360-3362
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the cerebral edema occurrence ,evolution and prognosis of intra-arterial thrombolytic recanali-zation in patients with acute ischemic stroke .Methods From October 2010 to October 2012 ,36 patients who underwent the intra-arterial thrombolytic therapy were cerebral recanalization .They were randomly divided into two groups :1-3 h group and >3-6 h group .The alteration of brain edema was observed by cranial CT .Their mRS .NHISS and BI were scaled and recorded before and after intra-arterial thrombolytic therapy .Results After intra-arterial thrombolytic therapy ,the occurrence rate of cerebral edema was 94% ,appeared at the onset of more than 1 hours in all patients .Long-term follow-up showed ,cerebral edema location appeared obvious cerebromalacia .Cerebral edema and clinical outcome had not significant difference between 1-3 h group and 3-6 h group . Conclusion Cerebral edema and loss of cerebral tissue occurred almost inevitability in patients who received intra-artery thromboly-sis and recanalized their cerebral artery .It indicates that good local circulation and general condition may be favorable factors that can gradually reduce brain edema .
