Tissue-engineered cartilage repair for sports-induced articular cartilage injury
10.3969/j.issn.2095-4344.2013.46.023
- VernacularTitle:组织工程化软骨修复运动性关节软骨损伤
- Author:
Luyao ZHANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2013;(46):8122-8127
- CountryChina
- Language:Chinese
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Abstract:
BACKGROUND:The emergence and development of tissue engineering technology provides a new idea for reconstruction of joint functions after sports-induced articular cartilage injuries, and realizes complete regeneration of cartilage tissue.
OBJECTIVE:To understand the basic principles of tissue engineering research, to analyze factors influencing tissue-engineered cartilage construction, and to explore the feasibility of tissue-engineered cartilage repair for sports-induced articular cartilage injury.
METHODS:Through the retrieval of literatures on the construction and application of tissue-engineered cartilage, we analyzed the feasibility of new cartilage formation in vivo using tissue engineering technology, focused on tissue-engineered cartilage construction and its application in cartilage injury and repair, thereby providing a theoretical basis for tissue-engineered cartilage repair of sports-induced cartilage injuries.
RESULTS AND CONCLUSION:Seed cells, scaf olds and in vitro culture environment constitute two elements of cartilage tissue engineering, which, as a whole, promote and restrict each other. The proper configuration of seed cells, scaf olds and in vitro culture environment is the key issue to be solved in the treatment of sports-induced cartilage injuries.
