Research progress of tissue factor pathway inhibitor-2 gene in non-small-cell lung cancer
10.3760/cma.j.issn.1006-9801.2013.10.020
- VernacularTitle:组织因子途径抑制物-2基因与非小细胞肺癌关系的研究进展
- Author:
Jiangshui LIANG
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-cell lung;
Tissue factor pathway inhibitor-2 gene
- From:
Cancer Research and Clinic
2013;25(10):714-716
- CountryChina
- Language:Chinese
-
Abstract:
Tissue factor pathway inhibitor-2 (TFPI-2) that inhibits plasmin,trypsin and matrix metalloproteinases is a broad-spectrum inhibitor of serine proteinase.TFPI-2 can accommodate the invasion and metastasis of human non-small-cell lung cancer by maintaining the integrity of extracellular matrix and regulating the angiogenesis and apoptosis of tumor cells.It has been a new target for gene therapy of cancers.
