Studies on Antibacterial Activity of Extracts from 60 Traditional Chinese Medicinals
10.11842/wst.2013.06.002
- VernacularTitle:60味中药提取物抗菌活性的研究
- Author:
Tiantian TONG
;
Hao HUANG
;
Yiming WANG
;
Guoan LUO
- Publication Type:Journal Article
- Keywords:
Antibacterial activity;
TCM extracts;
Bacillus subtilis;
Bacillus cereus;
Staphylococcus aureus
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2013;(6):1268-1273
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to screen antibacterial agents against 9 pathogenic bacteria from 240 extracts of 60 traditional Chinese medicinals ( TCM ) . And the minimum inhibitory concentration ( MIC ) test was applied on extracts with positive results. The disk diffusion was employed to screen the antibacterial activity preliminar-ily among 240 extracts. The MICs of active extracts were tested by liquid culture method (double dilution method). The results revealed that 104 extracts show antibacterial activity on one or more strains, 20 of them show strong inhibition on three commonly seen bacteria ( MIC < 0 . 2 mg/mL ) . It was concluded that ethanol , acetone and hexane extracts of 11 TCMs including Salvia miltiorrhiza, Cnidium monnieri, Polygonum tinctorium, Taraxacum mongolicum, Morus alba, Glycyrrhiza uralensis, Curcuma longa, Arnebia euchroma, Lobelia chinen-sis , Chrysanthemum indicum and Buddleja officinalis show strong inhibition on Bacillus subtilis , Bacillus cereus , Staphylococcus aureus .
