Effect of Pepper and Piper Longum on Hepatic Energy Metabolism Factors in Rats
10.11842/wst.2013.06.010
- VernacularTitle:胡椒、荜茇对正常大鼠肝脏能量代谢因子的影响
- Author:
Guangzhi CUI
;
Feng LI
;
Xiaoling SONG
;
Xiaoyan WANG
- Publication Type:Journal Article
- Keywords:
Pepper;
Piper longum;
rats;
hepatic energy metabolism
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2013;(6):1314-1317
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to explore the effect of heat-nature Chinese herbs of Pepper and Piper longum on hepatic energy metabolism of rats in order to research the impact of ratˊs physical activities with heat-nature Chinese herbs and establish the research foundation of Chinese herbal medicine nature . A total of 30 rats were randomly divided into three groups . Saline was given in the control group . Pepper water extract was given in the Pepper group . And Piper longum water extract was given in the Piper longum group . The administration dosage was 10 ml/kg intragastrically for 30 days . Changes of hepatic energy metabolism related enzymes were determined . The results showed that compared with the control group , Ca2+-ATPase , Ca2+-Mg2+-ATPase , and LDH enzyme of the Pepper group and Piper longum group were significantly increased . And the hepatic glycogen content was significantly reduced . It can obviously increase energy intake , digestible energy and metabolizable energy per body weight in rats . There was no statistical significance between the Pepper group and Piper longum group . It was concluded that the heat-nature Chinese herbs of Pepper and Piper longum can promote the decomposition of hepatic glycogen , increase the activity of LDH enzyme , Ca2+-ATPase , Ca2+-Mg2+-ATPase . It increases the consumption of ATPase in order to increase energy intake , digestible ener-gy and metabolizable energy per body weight in rats and promote the hepatic energy metabolism .
