Inhibitory Activity of α-Glucosidase from Extracts of Different Processed Salvia Miltiorrhiza Bunge . Products
10.11842/wst.2013.06.017
- VernacularTitle:丹参不同炮制品α-葡萄糖苷酶抑制活性
- Author:
Wei ZHANG
;
Zhenhua YIN
;
Tao PENG
;
Wenyi KANG
- Publication Type:Journal Article
- Keywords:
Salvia miltiorrhiza Bunge.;
processed products;
α-glucosidase;
inhibitory activity
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2013;(6):1348-1352
- CountryChina
- Language:Chinese
-
Abstract:
This article was aimed to evaluate the α-glucosidase inhibitory activity of extracts from the root of Salvia miltiorrhiza Bunge and different processed products. The α-glucosidase inhibitory activity was screened with acarbose as positive control and by α-glucosidase inhibitory model in v itro . The results showed that the ex-tracts from the root of S. miltiorrhiza and different processed products had inhibitory activity. And the activity was higher than that of acarbose. In addition to the MeOH extract of S. miltiorrhiza carbon, the inhibitory activity of MeOH extracts from other processed products were higher than that of MeOH extract of S. miltiorrhiza. The in-hibitory activity of petroleum ether extracts of different processed products were close to S. miltiorrhiza. EtOAC extracts were lower than that of S. miltiorrhiza. The n-BuOH extracts were higher than that of S. miltiorrhiza. The inhibitory activity of extracts was positively correlated with concentrations, and it depended on the concentra-tion. It was concluded that the processed products of S. miltiorrhiza can strengthen α-glucosidase inhibitory activ-ity in different degrees.