Orthogonal Test for Optimization of Qinshuang Particle Spray Granulation Process
10.11842/wst.2013.06.035
- VernacularTitle:正交试验优化芩双颗粒喷雾制粒工艺
- Author:
Hong JIANG
;
Guanghan WANG
;
Yi WU
;
Xianmin YOU
;
Xiaodong LV
- Publication Type:Journal Article
- Keywords:
Qinshuang particles;
spray granulation;
orthogonal test;
Baicalin
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2013;(6):1437-1440
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to optimize Qinshuang particle best spray granulation process conditions. The or-thogonal test method was used with grain yield and baicalin transfer rate as the inspection indexes. The main in-fluence factors of Qinshuang particle spray granulation process were investigated. The results showed that the best technological parameters are atomization pressure of 1 800 Pa, inlet temperature at 90°C - 100°C, outlet temper-ature at 50 ° C - 60 ° C , and the extract relative density of 1 . 10 ( 60 ° C ) . It was concluded that the reasonable pro-cess conditions make particles with stable quality, which provide the experimental basis for industrial production.
