Research progress of new anticancer drug lobaplatin in treatment of metastatic breast cancer
10.3760/cma.j.issn.1006-9801.2013.09.025
- VernacularTitle:抗肿瘤新药洛铂治疗转移性乳腺癌的研究进展
- Author:
Xu SUN
;
Donghu SUI
- Publication Type:Journal Article
- Keywords:
Lobaplatin;
Metastatic breast cancer;
Pharmacodynamics;
Clinical research
- From:
Cancer Research and Clinic
2013;25(9):646-648
- CountryChina
- Language:Chinese
-
Abstract:
As the third generation platinum antitumor drug with independent intellectual property rights,a number of basic and clinical research shows lobaplatin can effectively inhibit the proliferation of human breast cancer cell lines including triple-negative breast cancer in vivo.Compared with the cisplatinbased regimens,lobaplatin-based regimens have similar efficacy,and better safety profile.It becomes the new treatment option of metastatic breast cancer,and remains to be further study to optimize clinical rational drug use.
