Progress on the relationship between obesity and endothelial injury
10.3760/cma.j.issn.1673-4408.2013.06.011
- VernacularTitle:肥胖与血管内皮损伤研究进展
- Author:
Pengli BAO
- Publication Type:Journal Article
- Keywords:
Obesity;
Endothelial factor;
Progenitor cell
- From:
International Journal of Pediatrics
2013;40(6):579-582
- CountryChina
- Language:Chinese
-
Abstract:
The onset of irreversibility of cardiovascular diseases caused by obesity has showed a rising trend,the underlying cause of the disease is the endothelial damage.Injury caused by obesity through four aspects:systolic and diastolic imbalance,anticoagulant and procoagulant imbalance,growth factors and growth factor imbalances and endothelial progenitor cell changes in endothelial damage.This paper reviews the reason and the mechanism of the endothelial damage through the change of the endothelial factors and progenitor cells.