Progress of KL-6 in pulmonary disease
10.3760/cma.j.issn.1673-4408.2013.06.007
- VernacularTitle:KL-6在肺部疾病中的研究进展
- Author:
Yuting ZHU
- Publication Type:Journal Article
- Keywords:
KL-6;
Interstitial lung disease;
Acute lung injury;
Tumor
- From:
International Journal of Pediatrics
2013;40(6):565-568
- CountryChina
- Language:Chinese
-
Abstract:
Krebs von den Lungen-6(KL-6) is a high-molecular-weight transmembrane mucin.In recent research,the levels of KL-6 in serum and bronchoalveolar lavage fluid are significantly higher in some pulmonary disease such as interstitial lung disease,acute lung injury,tumor and bronchopulmonary dysplasia.Consequently KL-6 is recommended as a reference index for early diagnosis,evaluation of therapeutic efficiency and outcome prediction.But the molecular mechanism of KL-6 in different diseases requires further research.
