Progress of Survivin gene in cancer
10.3760/cma.j.issn.1006-9801.2013.09.023
- VernacularTitle:Survivin基因与肿瘤的研究进展
- Author:
Weiwei SHI
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Survivin gene;
Polymorphism
- From:
Cancer Research and Clinic
2013;25(9):640-642
- CountryChina
- Language:Chinese
-
Abstract:
Survivin is an apoptosis inhibitor and plays an important role in the development and progression of cancer.It is undetectable in normal adult tissues,but has been showed to be overexpressed in various cancers and has been regarded as a marker of malignancy.And the promoter polymorphism of Survivin gene is closely related to risk of cancer and gene susceptibility,this might provide clues for further elucidation of the correlation of risk of cancer and genetic polymorphism,and for diagnosis,prevention and screening of cancer gene.
