Determination of Emodin and Chrysophanol in Shutongantai Capsules by HPLC
10.3969/j.issn.1005-5304.2013.11.023
- VernacularTitle:HPLC测定舒通安泰胶囊中大黄素和大黄酚的含量
- Author:
Jianzhong HOU
;
Lijian YU
;
Cheng YANG
- Publication Type:Journal Article
- Keywords:
Shutongantai Capsules;
HPLC;
emodin;
chrysophanol;
content determination
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2013;(11):61-62
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a quality standard of Shutongantai Capsules. Methods Thermo C18 column was used with methanol-0.1% phosphoric acid as mobile phase. The flow rate was 1.0 mL/min, detection wavelength was 254 nm, and column temperature was 30 ℃. Results Emodin showed a good linear relationship in the range of 0.016-0.080 μg (r=0.999 6). Chrysophanol showed a good linear relationship in the range of 0.032-0.160 μg (r=0.999 8). Conclusion The established method is simple, feasible and reproducible, and can be used for the quality control of Shutongantai Capsules.
