Research progress of the mechanism in bone destruction caused by neuroblastoma
10.3760/cma.j.issn.1673-4408.2013.06.004
- VernacularTitle:神经母细胞瘤引起骨破坏机制的研究进展
- Author:
Teng HAO
- Publication Type:Journal Article
- Keywords:
Neuroblastoma;
Bone destruction;
Cytokines
- From:
International Journal of Pediatrics
2013;40(6):555-557
- CountryChina
- Language:Chinese
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Abstract:
Neuroblastoma is one of the solid tumors in children which easily metastasizes to bone.It causes radiographic appearance of osteoclastic reactions after bone metastases.In the process,neuroblastoma cells,osteoblasts and bone stromal cells secrete a series of related factors to promote bone metastases.In this paper,the progress of the mechanism in bone destruction caused by neuroblastoma is reviewed.
