Role and mechanism of XRCC4 in the genesis and development of tumor
10.3760/cma.j.issn.1673-4203.2013.10.016
- VernacularTitle:XRCC4在肿瘤发生发展中的作用及机制
- Author:
Liwei WANG
;
Liming ZHENG
- Publication Type:Journal Article
- Keywords:
XRCC4;
Neoplasms;
SNPs
- From:
International Journal of Surgery
2013;40(10):699-702
- CountryChina
- Language:Chinese
-
Abstract:
DNA double-strand breaks(DSBs) repair protein XRCC4,plays an important role in the genesis and development of tumor,there are many different aspects in the tumor genesis and development.This paper reviews the molecular mechanism of XRCC4 in repairing DSBs,several theories of tumor genesis and development,and the relationship between XRCC4 gene's single nucleotide polymorphisms(SNPs) and tumor.
