MRI evaluation of prognosis for hypoxic ischemic encephalopathy in term neonates

VernacularTitle:足月新生儿缺氧缺血性脑病的脑部磁共振成像随访及预后评估
Author: Jun WU ; Ruixia XU ; Guixiu YI
Publication Type:Journal Article
Keywords: hypoxic-ischemic encephalopathy; magnetic resonance imaging; prognosis; neonates
From: Journal of Clinical Pediatrics 2013;(11):1024-1028
CountryChina
Language:Chinese
Abstract: Objectives To explore the characteristics and value of magnetic resonance imaging (MRI) in predicting prognosis of hypoxic ischemic encephalopathy (HIE) in neonatal period, at 4 months and 4 years old. Methods Twenty-four patients with HIE were examined by MRI. Their MRI results in the neonatal period, at month 4 and year 4 and neurological functions at year 4 were compared. Results Periventricular signal alterations and deep gray matter involvement were common in HIE neonates. The neonates with deep gray matter involvement usually had neurological malfunction and poor prognosis. The patients with encephalomalacia and periventricular leukomalacia at 4 months and 4 years old also had poor prognosis. The abnormal MRI ifndings in HIE children at 4 month and 4 year old predicted the occurrence of neurological malfunction. Con-clusions The MRI of infant at 4 months old is important in prediction of neurological malfunction and provides guidance of clinical intervention for children with HIE.