Study on Quality Standard of Tongluo Tangtai Granules
10.3969/j.issn.1005-5304.2013.12.015
- VernacularTitle:通络糖泰颗粒质量标准研究
- Author:
Qing HU
;
Ying SONG
;
Caiyan LIU
;
Jing TAN
- Publication Type:Journal Article
- Keywords:
Tongluo Tangtai Granules;
TLC;
HPLC;
berberine;
quality standard
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2013;(12):39-41
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the quality standard for Tongluo Tangtai Granules. Methods TLC was applied to the qualitative identification of Rhizoma Coptidis, Semen Sinapis Albae and Radix Scrophulariae, and HPLC was applied to the quantitative determination of berberine in the prescription. Results Rhizoma Coptidis, Semen Sinapis Albae and Radix Scrophulariae could be detected by TLC, the spots were clear and there was no interference for the negative sample. A good linearity of berberine was showed in the range of 0.037 29-2.610 3 μg (r=1.000 0). The average recovery of berberine was 98.85%, and RSD was 0.70% (n=6). Conclusion The methods are simple, sensitive, accurate with good reproducibility. It can be used for the quality control of Tongluo Tangtai Granules.
