The relationship between time to relapse and survival after curative surgery in colorectal cancer patients
10.3969/j.issn.1007-3969.2013.10.010
- VernacularTitle:结直肠癌根治性手术后复发时间与生存时间的相关性分析
- Author:
Yuanhe WANG
;
Jin ZHOU
;
Yujia GAO
;
Yu TANG
;
Xiujuan TAO
;
Ying ZHAO
- Publication Type:Journal Article
- Keywords:
Colorectal cancer;
Time to relapse;
Overall survival
- From:China Oncology
2013;(10):841-844
- CountryChina
- Language:Chinese
-
Abstract:
Background and purpose:The risk of recurrence for colorectal cancer after curative surgery is up to 30%-40%. We aimed to evaluate the relationship between time to relapse (TTR) of colorectal cancer with clinical pathological parameters and overall survival after recurrence. Methods:We carried out the analysis of clinical data, pathological examination and follow up information of 375 colorectal cancer patients who admitted to Liaoning Cancer Hospital. Patients were categorized into relapse at<2, 2-5 and>5 years following their initial surgery. Results:TTR was associated with the clinical stage at diagnosis and liver or lung metastasis status. Short TTR (<2 years) was positively associated with survival. However, there was no significant difference in survival between patients who relapsed at 5 years or later compared with those who relapsed between 2 and 5 years. Conclusion:TTR within 2 years is an important predictor of shorter survival for colorectal cancer patients who experienced a relapse.
