The mechanism of action of probiotics on intestinal mucosal barrier
10.3760/cma.j.issn.1673-4408.2013.05.016
- VernacularTitle:益生菌对肠黏膜屏障的作用机制
- Author:
Nan LIN
- Publication Type:Journal Article
- Keywords:
Probiotics;
Intestinal mucosa;
Tight junctions;
Mucins;
Immunity;
Defensin;
Bacterial adhesion
- From:
International Journal of Pediatrics
2013;40(5):493-496
- CountryChina
- Language:Chinese
-
Abstract:
Intestinal mucosal barrier has the function to isolate intestinal contents and internal environment,prevent foreign antigens and pathogens invading to lamina propria mueosae and can maintain organic homeostasis and normal activities.Impairment of the intestinal barrier is a key event in various gastrointestinal diseases.Probiotics are live microorganisms which ingested and reach the intestines in sufficient numbers to confer benefit to the host.It can improve or prevent many gastrointestinal diseases.The main reason is probiotics can maintain intestinal barrier function in various paths.This paper reviews its mechanisms of action.
