Clinical observation on 308-nm monochromatic excimer light for the treatment of amelanotic nevus
10.3760/cma.j.issn.0412-4030.2013.10.020
- VernacularTitle:308单频准分子紫外光治疗无色素痣的临床疗效观察
- Author:
Huijun MA
;
Lianjin SONG
;
Yang YANG
;
Rong HU
;
Mingyue ZHANG
;
Pengfei GAO
;
Jingyi WANG
- Publication Type:Journal Article
- From:
Chinese Journal of Dermatology
2013;46(10):751-752
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of 308-nm monochromatic excimer light for the treatment of amelanotic nevus.Methods Eighteen patients with amelanotic nevus were treated with 308-nm monochromatic excimer light twice a week for five consecutive weeks.Melanin content index (MCI) was measured in the lesions before and after the treatment.After the final exposure,a three-month follow-up was carried out.Results After the start of treatment,the MCI in lesions increased in a session-dependent manner and approximated to 100% of that in perilesional normal skin after six sessions of treatment.The follow-up revealed a decrease trend in MCI after the end of the treatment,which was nearly equal to that in perilesional normal skin one month later,and dropped to about 90% of that three months later.No side effects such as blisters or scar were observed during the treatment.Conclusions The 308-nm monochromatic excimer light is safe and effective for the treatment of amelanotic nevus.Re-exposure to 308-nm monochromatic excimer light after three months is recommended as consolidation therapy.