Signal transducers and activators of transcription(STAT) family and pathogenesis of asthma
10.3760/cma.j.issn.1673-4912.2013.05.033
- VernacularTitle:信号传导子和转录激活子家族与支气管哮喘发病机制的研究进展
- Author:
Nan ZHANG
;
Simin WAN
;
Suwan ZHANG
- Publication Type:Journal Article
- Keywords:
STAT family;
Bronchial asthma
- From:
Chinese Pediatric Emergency Medicine
2013;20(5):535-537
- CountryChina
- Language:Chinese
-
Abstract:
Bronchial asthma(asthma for short) is a chronic inflammatory disease of the lung,which is involved with various cells and cytokines.Now,the related genes of asthma is not well-known yet.But research shows that there are related genes to airway hyperreactivity,IgE regulation and atopic reaction.These genes play an important role in asthma.In recent years,it is recognized that STAT family plays an important role in inflammatory and immunological diseases.In this article the role of STAT family played in asthma pathogenesis will be reviewed.
