Prognostic factors analysis of 133 patients with brain glioma

VernacularTitle:133例脑胶质瘤患者预后因素分析
Author: Junbao WEI ; Xiaodong ZHU ; Long CHEN ; Yunli YANG ; Jiangqiong HUANG ; Yingxin LIU
Publication Type:Journal Article
Keywords: glioma; postoperative radiotherapy; prognostic factors
From: Chongqing Medicine 2013;(32):3908-3910
CountryChina
Language:Chinese
Abstract: Objective To explore the prognosis and related factors of brain glioma .Methods 133 patients who have been con-firmed pathology with brain glioma from Jan .2001 to Dec .2010 were retrospectively analyzed .The factors such as sex ,age ,func-tional status ,histological character ,the longest diameter of tumor ,surgical excision of part or all of the tumor ,whether or not being radiotherapy after surgical excision were selected to evaluate by single factor and multiple factors analysis .Results The median fol-low-up time was 36 months ,The follow-up rate was 93% .73 cases were followed up for 3 years ,the 1- ,2- and 3- year survival rate was 93% ,82% and 70% ,respectively ,the median survival time was 62 .7 months .Multiple factors regression analysis showed that histological character ,the longest diameter of tumor and whether or not being radiotherapy after surgical excision were related to prognosis .Conclusion High-grade of histological character ,the longest diameter of tumor≥6 cm predict poor prognosis ,postop-erative radiotherapy can improve the survival of glioma .