The value of myocardial enzymes and cerebrospinal fluid examination in diagnosis of hand, foot and mouth disease complicated with SIRS and MODS
10.3969/j.issn.1671-8348.2013.31.001
- VernacularTitle:心肌酶谱和脑脊液检查诊断手足口病并发SIRS和MODS的价值分析
- Author:
Jianxiong ZHAO
;
Aizhong WANG
- Publication Type:Journal Article
- Keywords:
hand,foot and mouth disease;
systemic inflammatory response syndrome;
multiple organ failure;
myocardial en-zymes;
cerebrospinal fluid
- From:
Chongqing Medicine
2013;(31):3721-3723
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of myocardial enzymes and cerebrospinal fluid examination in diagnosis of hand , foot and mouth disease(HFMD) complicated with systemic inflammatory response syndrome (SIRS) and multi-organ dysfunction syndrome(MODS) .Methods During April 2010 to January 2013 ,204 cases were retrospectively analyzed and checked myocardial enzymes and cerebrospinal fluid examination of the children to analyze the correlation between inspection results and incidence of SIRS and MODS .Results The incidence of SIRS and MODS and mortality rate of severe and critical group was significantly higher than ordinary group(P<0 .05) .CSF protein ,CK-MB ,LDH and cTnT content of SIRS group were significantly higher than non-SIRS group(P<0 .05) .CSF protein ,CK-MB ,LDH and cTnT content of MODS group were significantly higher than non-MODS group(P<0 .05) .Spearman rank correlation analysis showed that CSF protein ,CK-MB and cTnT was positively correlated to inci-dence of SIRS and MODS(P<0 .05 ,P<0 .05) .Conclusion Myocardial enzymes and cerebrospinal fluid examination have a higher value in diagnosis of HFMD complicated with SIRS and MODS .
