Clinical Study on Serum Homocysteine,B12 Folic Acid and Gestational Diabetes Mellitus

VernacularTitle:血清同型半胱氨酸、维生素B12、叶酸与妊娠期糖尿病的临诊研究
Author: Xiaohang HUA
Publication Type:Journal Article
Keywords: diabetes; pregnant; Hcy; VitB12; FA
From: Journal of Zhejiang Chinese Medical University 2013;(11):1322-1323
CountryChina
Language:Chinese
Abstract: [Objective] To explore the levels of folic acid(FA), vitamin(Vit) Bl2 and homocysteine(Hcy) of gestational diabetes mel itus(GDM) patients and the relation among them. [Method] Select 40 GDM cases from our hospital diagnosed with oral glucose tolerance test(0GTT) and 40 healthy pregnant women in the same period, take circulation enzymic method to test Hcy concentration, and take chemiluminescence to measure FA and VitBl2. [Result] GDM patients’Hcy level is in negative relation with VitBl2 and FA levels. Comparing GDM patients’serum Hcy,VitBl2 and FA with normal pregnant group,Hcy level is raised much(P<0.01), FA and VitBl2 are reduced markedly(P<0.01). In later period of GDM pregnancy, they have high Hcy, lack of FA and Vit-Bl2; the pregnancy hypertension shal strengthen the intake of VitBl2 and FA, as wel as have periodical supervision, to reduce Hcy level and decrease the side effects on fetus and injury to pregnant women’s great vessels and micro-vessels.