Chemical Constituents from Roots of Angelica apaensis with Cytotoxic Activity
- VernacularTitle:阿坝当归的化学成分及体外抗肿瘤活性研究
- Author:
Yong LI
;
Weijian GUANG
;
Xue WU
;
Xia LIU
;
Min LUO
;
Xian LI
- Publication Type:Journal Article
- Keywords:
Angelica apaensis;
Linear furocoumarins;
Cytotoxicity
- From:
Journal of Kunming Medical University
2013;(11):1-4
- CountryChina
- Language:Chinese
-
Abstract:
Objective Obtaining chemical constituents of Angelica apaensis collected in Qiaojia County of Yunnan Province and detecting their anti-tumor activities in vitro. Methods The MeOH extract of was repeatedly subjected to column chromatography over silica gel, Sephadex LH-20 and/or RP-18 and semipreparative HPLC. Their anti-tumor activities in vitro were measured by MTT colorimetric assay. Results Eight compounds were isolated from the roots of this plant. Conclusion The major type of chemical constituents of in Yunnan is furocoumarin. These separated compounds showed weak anti-tumor activity in vitro.
