Correlation Study of the Expression of XRCC1 to the Effect of Radiotherapy in Gliomas
- VernacularTitle:XRCC1在脑胶质瘤中的表达及与放疗的相关性研究
- Author:
Huatao NIU
;
Lin LUO
;
Zaoxiu HU
;
Hongping YUAN
;
Pin ZUO
;
Yaodong FAN
- Publication Type:Journal Article
- Keywords:
Glioma;
XRCC1;
Radiotherapy
- From:
Journal of Kunming Medical University
2013;(11):29-32
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the expression of XRCC1 and glioma. Methods Total of 26 samples of glioma were divided into 4 groups:gradeⅠ,gradeⅡ,gradeⅢand gradeⅣ. The expression of XRCC1 in 26 Gliomas tissues were examined using SP immunohistochemical staining.Results The positive staining of XRCC1 protein was localized in nucleus of tumor cells in Glioma. There was no correlation among them. The difference of XRCC1 expression among gradeⅠ~Ⅳ was not significant ( >0.05) .Conclusion The difference of XRCC1 expression among gradeⅠ~Ⅳ was not significant. The expression of XRCC1 was closely correlated with the effect of radiotherapy.
