Effects of anti-tumor drugs on myeloid-derived suppressor cells
10.3760/cma.j.issn.1673-422X.2013.09.005
- VernacularTitle:抗肿瘤药物对髓系来源抑制性细胞的影响
- Author:
Tian WANG
;
Xiaohua LIANG
- Publication Type:Journal Article
- Keywords:
Myeloid cells;
Antineoplastic agents;
Immunosuppressive agents;
Myeloied derived suppressor cells
- From:
Journal of International Oncology
2013;40(9):655-658
- CountryChina
- Language:Chinese
-
Abstract:
Myeloid-derived suppressor cells (MDSCs) play an important immunosuppressive role during the tumor development process.And the progression of many tumors are always accompanied with abnormal accumulation of MDSCs.Moreover,both the accumulation and functions of MDSCs could be affected by complicated factors.Therefore,how to effectively reduce the immunosuppressive effects of MDSCs in oncotherapy has become the focus of scholars.Recent studies show that anti-tumor drugs can affect many biological behaviors of MDSCs.
