Solitary Plasmacytoma associated with Peripheral Neuropathy.
- Author:
Sook Young RHO
1
;
Keun Ho CHEONG
;
Phil Za CHO
;
Sang Cheol PARK
Author Information
1. Department of Neurology, National Medical Center, Korea.
- Publication Type:Case Report
- MeSH:
Axons;
Biopsy;
Demyelinating Diseases;
Humans;
Korea;
Male;
Middle Aged;
Mucous Membrane;
Multiple Myeloma;
Myelin Sheath;
Neoplasms, Plasma Cell;
Peripheral Nervous System Diseases*;
Plasma Cells;
Plasmacytoma*;
Radiotherapy;
Sural Nerve
- From:Journal of the Korean Neurological Association
1994;12(3):527-533
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Solitary plasmacytoma, in contrast to the disseminated neoplastic proliferation of plasma cells with marked infiltration of multiple organ system in multiple myeloma, is plasma cell neoplasm of a single focus occuring either in bone or soft tissue. The association between a solitary plasmacytoma and peripheral neuropathy is rare, and it is a progressive sensorimotorneuropathy, with a raised CSF protein and mixed demyelination and axonal loss in nerve biopsy. Localized radiotherapy indeed proves to be effective of not only arresting the progress of the neuropathy but also allowing a degree of recovery. We experienced a 55-year-old male with a solitary plasmacytoma and peripheral neuropathy confirmed by the radiologic studies, immunohistochemical stain of nasopharyngeal mucosa biopsy and sural nerve biopsy, which has loss of myelinated fiber and axonal degeneration. Until now, the reported cases are very rare in Korea, so we presented a case of solitary plasmacytoma associated with peripheral neuropathy.
