A Case of Suspected Post-Irradiation Delayed Necrotizing Leukoencephalopathy.
- Author:
Jeong Gyun NA
1
;
Won Young JUNG
;
Kyung Won CHO
Author Information
1. Department of Neurology, Chosun University Medical College, Korea.
- Publication Type:Case Report
- MeSH:
Cranial Nerve Diseases;
Leukoencephalopathies*;
Magnetic Resonance Imaging;
Nervous System;
Peripheral Nervous System;
Peripheral Nervous System Diseases;
Quadriplegia;
Radiation Injuries;
Spinal Cord Diseases;
Urinary Incontinence
- From:Journal of the Korean Neurological Association
1994;12(3):534-541
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Therapeutic irradiation may produce a variety of adverse side effects on the central and the peripheral nervous systems. These adverse effects are divided into two main groups; transient and permanent. Four major clinical syndromes have been described in relation to permanent radiation injury of the nervous system: encephalopathy, cranial neuropathy, myelopathy, and peripheral neuropathy. Among them, delayed encephalopathy represents the major hazard in CNS irradiation. The characteristic MR imaging pattern of radiation induced delayed necrotizing leukoencephalopathy is symmetric, high-signal foci on T2WI in the periventricular white matter. We report a case of suspected post-irradiation leukoencephalopathy showed progressive mental change, quadriparesis, and urinary incontinence with characteristic MR findings who had taken therapeutic irradiation 12 months ago.
