Logic Problem Analysis on Determination of Syndrome-attribution in A Variety of Animal Model Establishment Methods
10.11842/wst.2013.07.033
- VernacularTitle:多种方法造模动物模型证属性判定逻辑问题剖析
- Author:
Jie CHU
;
Maoxin LIANG
- Publication Type:Journal Article
- Keywords:
Animal model;
pathogen-modeling;
modern medical modeling method;
objective index;
determine of syndrome-attribution
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2013;(7):1665-1669
- CountryChina
- Language:Chinese
-
Abstract:
Intervening animals by pathogen of traditional Chinese medicine (TCM) to establish animal model is the most common and easiest method to determine syndrome attribute of an animal model. However, the underlying prob-lem of this modeling method is that the concept of wind, cold and dampness in the nature are confused with the syn-drome of wind-cold-dampness summarized by abnormal appearance of clinical patients. The typical animal model establishment are through the methods of wind blowing, low temperature freezing, cold water immersion, environmen-tal humidity increasing. Modern medical modeling methods, such as chemicals, organ resections, are also used in the establishment of animal models. Then, the syndrome-attribution of modeling animal is evaluated by physicochemical indexes of modern medicine which is one of modeling methods that have been used by academia in early times. But animal model established by this method is a kind of disease model which is lack of sufficient theoretical and clini-cal evidences. Therefore, the syndrome-attribution should be reappraised among this kind of animal models.
