Hypoxia-inducible factor-1 and transforming growth factor-β in tumor
10.3760/cma.j.issn.1673-422X.2013.09.004
- VernacularTitle:低氧诱导因子-1及转化生长因子-β与肿瘤
- Author:
Chao GAO
;
Xiangying FENG
- Publication Type:Journal Article
- Keywords:
Hypoxia-inducible factor-1;
Transforming growth factor-β;
Neoplasms;
Vascular endothelial growth factors
- From:
Journal of International Oncology
2013;40(9):652-655
- CountryChina
- Language:Chinese
-
Abstract:
Hypoxia-inducible factor-1 (HIF-1) is one of the most important hypoxia signal transmission factor,and it has been observed in many human tumors.HIF-1 could play a role of promoting tumor by regulating the expression level of transforming growth factor-β in vivo and in vitro,and then affecting the development and prognosis of tumor.
