Serum thymidine kinase 1 and cancer
10.3760/cma.j.issn.1673-422X.2013.09.001
- VernacularTitle:血清胸苷激酶1与肿瘤
- Author:
Wenjing XU
;
Degan LIU
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Thymidine kinase;
Immunohistochemistry
- From:
Journal of International Oncology
2013;40(9):643-645
- CountryChina
- Language:Chinese
-
Abstract:
Thymidine kinase 1 (TK1),an enzyme of the pyrimidine remedial pathway,can catalyze phosphorylation of thymidine to thymidine monophosphate.It is closely related to cell cycle regulation and cell proliferation.A number of experiments show that TK1 can be used for physical examination,tumor screening,routine testing,effect monitoring and prognosis evaluation,which is considered to be a sensitive and useful marker for human tumor growth.