Influence of vitamin E on skeletal muscle injury of rats after eccentric exercise
10.3760/cma.j.issn.1672-7088.2013.27.005
- VernacularTitle:口服Vitamin E对离心运动后大鼠骨骼肌损伤的影响
- Author:
Yinxin WU
;
Haiping ZHANG
;
Yan GAO
;
Shenglin SU
- Publication Type:Journal Article
- Keywords:
Vitamin E;
Eccentric exercise;
Skeletal muscle of rats;
MDA;
SOD
- From:
Chinese Journal of Practical Nursing
2013;29(27):11-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective From the angle of skeletal muscle ultrastructure and free radical metabolism,the paper explored the effect of vitamin E on skeletal muscle's damage after eccentric exercise.Methods 48 male Sprague Dawley rats were randomly divided into the control group,the sport group,the physiological saline group,and the vitamin E group.The model of animals was made by a bout of eccentric exercise on a treadmill.After the training,triceps brachiies were extracted from the right side of rats.Parts of triceps brachiies were made for microelectric slices,the others for the extracting of SR by the method of centrifugation at different speeds and for measuring the content of MDA and activity of SOD.Results In the vitamin E group,the muscular ultrastructures damage were improved obviously compared with that of the physiological saline group.Meanwhile,the value of MDA in the vitamin E group was greatly decreased and activity of SOD was notably increased compared with the sport group and the physiological saline group,but still worse than those of the control group.Conclusions Supplying of vitamin E could decrease the content of MDA in SR of skeletal muscle,increase the activity of SOD,then further relieve the effect of free radical on athletic injury.
