Distribution of the hormone-sensitive lipase gene i6 polymorphism in Zunyi region
- VernacularTitle:遵义地区人群激素敏感脂肪酶基因i6多态性分布
- Author:
Bin GE
;
Jian LU
;
Xueying LI
- Publication Type:Journal Article
- Keywords:
hormone-sensitive lipase;
gene polymorphism distribution
- From:
Basic & Clinical Medicine
2009;29(11):1194-1197
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the polymorphism distribution of the hormone-sensitive lipase (HSL) gene i6 in Zunyi region. Methods HSL i6 in the Zunyi population was examined with ploymerase chain reaction-single strand conformation polymorphism (PCR-SSCP), and analyzed for its distribution. Results Six different alleles and 11 different genotypes were found in the HSL i6. The PIC is more than 0.7, in which allele 6 and allele 7 were most widely distributed. Conclusion The polymorphism of HSL i6 was identified and the result suggests in Zunyi HSL as a candidate gene of glucose and lipid metabolism.
