Rituximab treatment of systemic lupus erythematosus associated pulmonary arterial hypertension:a new insight
- VernacularTitle:利妥昔单抗治疗系统性红斑狼疮相关肺动脉高压的前景
- Author:
Wei WANG
;
Qian WANG
;
Jiuliang ZHAO
;
Mengtao LI
;
Xiaofeng ZENG
- Publication Type:Journal Article
- Keywords:
rituximab;
pulmonary arterial hypertension;
systemic lupus erythematosus
- From:
Basic & Clinical Medicine
2010;30(3):317-319
- CountryChina
- Language:Chinese
-
Abstract:
Pulmonary arterial hypertension(PAH) is one of the most severe complications of systemic lupus erythematosus(SLE).Recent studies emphasized the role of T and B lymphocytes in the pathogenesis of PAH.Rituximab (RTX),not only targeting at B lymphocytes,but also been proven to affect T cells,thus could be a potential treatment for SLE-PAH.
