Roles of carcinoembryonic antigen-related adhesion molecules in lung cancer
10.3760/cma.j.issn.1673-422X.2013.10.014
- VernacularTitle:癌胚抗原相关黏附分子在肺癌中的作用
- Author:
Xiuxiu WANG
;
Xiaojie ZHANG
;
Hua ZHANG
- Publication Type:Journal Article
- Keywords:
Carcinoembryonic antigen-related adhesion molecules;
Lung neoplasms;
Prognosis
- From:
Journal of International Oncology
2013;40(10):765-768
- CountryChina
- Language:Chinese
-
Abstract:
Carcinoembryonic antigen-related adhesion molecules (CEACAMs) belong to the immunoglobulin superfamily.Related studies show that CEACAMs play critical roles in the occurrence and development,and are closely related to the prognosis of lung cancer.Recently,it has made some progresses in the studies by using monoclonal antibodies,single domain antibodies,RNA interference,gene knockout and other technical means targeting different epitopes of CEACAMs in lung cancer,suggesting CEACAMs may become new diagnostic biomarkers and therapeutic targets of lung cancer.
