Application of attenuated salmonella in the gene treatment of tumor
10.3760/cma.j.issn.1673-422X.2013.10.009
- VernacularTitle:减毒沙门菌在肿瘤基因治疗中的应用
- Author:
Pengfei LI
;
Junzhong SUN
- Publication Type:Journal Article
- Keywords:
Attenuated salmonella;
Neoplasms;
Vaccine carrier;
Damage repairment
- From:
Journal of International Oncology
2013;40(10):748-751
- CountryChina
- Language:Chinese
-
Abstract:
Salmonella is a kind of intracellular invasive facultative anaerobe,maintaining its antigenicity after being attenuated.Now,it has been widely used as a transporter of DNA vaccines.Salmonella carrying related antigen gene can inhibit multiple tumors,and salmonella carrying repair gene has a clear repair effect for the organism injury after chemoradiotherapy.
