Research about NNMT gene in cancer
10.3760/cma.j.issn.1673-422X.2013.10.004
- VernacularTitle:NNMT基因在肿瘤中的研究
- Author:
Weimin ZHOU
;
Kuangbiao ZHONG
;
Ming GUI
- Publication Type:Journal Article
- Keywords:
Nicotinamide N-methyltransferase;
Nicotinamide;
Neoplasms
- From:
Journal of International Oncology
2013;40(10):732-735
- CountryChina
- Language:Chinese
-
Abstract:
Nicotinamide N-methyltransferase (NNMT) is a S-adenosyl-L-methionine (SAM) dependent cytoplasm enzyme,which plays a vital role in the biotransformation and detoxification of many drugs and xenobiotic compounds.Recent studies have revealed abnormal expression of NNMT in many tumors,which may contribute to tumorigenesis and tumor development and radiotherapy or chemotherapy resistance.
