Advances in the treatment of aggressive non-Hodgkin's lymphoma

VernacularTitle:侵袭性非霍奇金淋巴瘤治疗进展
Author: Junjiao GU ; Yanyan LIU
Publication Type:Journal Article
Keywords: Lymphoma,non-Hodgkin; Drug therapy; Radiotherapy; Molecular targeted therapy
From: Journal of International Oncology 2013;40(9):705-707
CountryChina
Language:Chinese
Abstract: As recent researches suggested,the continuous infusion and novel targeted medicines have been expected to improve the outcome of patients with aggressive B-cell non-Hodgkin's lymphoma.Nevertheless,it does not improve the curative effect by increasingly intensive dosage.Patients with aggressive T-cell non-Hodgkin's lymphoma have present better prognosis recently,which is attributed to better efficacy of the modified regimens in patients with NK/T cell lymphoma.Multiple genetic abnormalities are implicated in poorer prognosis in patients with aggressive T-cell non-Hodgkin's lymphoma.Non-myeloablative allogeneic stem cell transplantation and new targeted drugs have improved the curative effects.Radiotherapy with modern technology also is expected to become an important means to improve outcomes of aggressive non-Hodgkin's lymphoma.