Value of Diffusion-weighted Imaging in Distinguishing Prostate Cancer from Benign Prostatic Hyperplasia:a Meta-analysis
10.3969/j.issn.1005-5185.2013.06.018
- VernacularTitle:磁共振扩散加权成像鉴别诊断前列腺癌与良性前列腺增生的Meta分析
- Author:
Lina SUN
;
Qiancheng LI
;
Kailiang CHENG
;
Mengchao ZHANG
;
Yunxia LIU
- Publication Type:Journal Article
- Keywords:
Prostatic neoplasms;
Diffusion magnetic resonance imaging;
Diffusion weighed imaging;
Apparent diffusion coefficient;
Meta analysis
- From:
Chinese Journal of Medical Imaging
2013;(6):464-467
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To explore the ADC value in distinguishing prostate cancer (PCa) and benign prostatic hyperplasia (BPH) by reviewing related articles. Materials and Methods The studies about the diffusion-weighted images in distinguishing the prostate cancer and benign prostatic hyperplasia were enrolled from the websites of Elsevier Science, PubMed, Springer-Link, Wiley Online Library, Medline and CNKI from 2000 to 2011, with DWI, prostate, cancer, carcinoma and hyperplasia as search terms. According to the uniform inclusion and exclusion criteria, the correct studies were chosen and the parameters including the mean values and standard deviations of ADC value were extracted. Meta-analysis was done by using Stata 11 software. Results A total of 7 studies met the inclusion criteria, including 4 English articles and 3 Chinese articles. The fixed-effect model was used due to no heterogeneity. The standardized mean difference (SMD) was-1.357 and 95%confidence interval (95%CI) was (-1.604,-1.109, P=0.000). Conclusion DWI can be helpful in distinguishing the prostate cancer from the benign prostatic hyperplasia, and the ADC value of PCa is lower than that of BPH.
