Muscular Sarcoidosis Detected by F-18 FDG PET/CT in a Hypercalcemic Patient.
10.3346/jkms.2013.28.9.1399
- Author:
Eun Ji HAN
1
;
Yi Sun JANG
;
In Suk LEE
;
Jong Min LEE
;
Siwon KANG
;
Hye Soo KIM
Author Information
1. Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Case Reports
- Keywords:
Muscular Disease;
Sarcoidosis;
Hypercalcemia;
Fluorine-18 Fluorodeoxyglucose;
Positron Emission Tomography
- MeSH:
Female;
Fluorodeoxyglucose F18/*diagnostic use;
Humans;
Hypercalcemia/complications/*diagnosis;
Kidney Calculi/complications/diagnosis;
Lymph Nodes/radionuclide imaging;
Middle Aged;
Positron-Emission Tomography;
Radiopharmaceuticals/*diagnostic use;
Sarcoidosis/complications/drug therapy/*radionuclide imaging;
Steroids/therapeutic use;
Tomography, X-Ray Computed
- From:Journal of Korean Medical Science
2013;28(9):1399-1402
- CountryRepublic of Korea
- Language:English
-
Abstract:
Sarcoidosis is a systemic granulomatous disease of unknown etiology that involves many organs, occasionally mimicking malignancy. We herein report a 50-yr-old woman of muscular sarcoidosis of chronic myopathic type, manifested by hypercalcemia and muscle wasting. Besides insignificant hilar lymphadenopathy, her sarcoidosis was confined to generalized atrophic muscles and therefore, F-18 FDG PET/CT alone among conventional imaging studies provided diagnostic clues for the non-parathyroid-related hypercalcemia. On follow-up PET/CT during low-dose steroid treatment, FDG uptake in the muscles disappeared whereas that in the hilar lymph nodes remained. PET/CT may be useful in the evaluation of unexpected disease extent and monitoring treatment response in suspected or known sarcoidosis patients.