The application of Primovist in liver cirrhosis and small hepatocellular carcinoma
10.3760/cma.j.issn.1007-8118.2013.12.020
- VernacularTitle:钆塞酸二钠在肝硬化性结节及小肝癌评估中的应用进展
- Author:
Lin LUO
;
Hong SHAN
;
Jin WANG
- Publication Type:Journal Article
- Keywords:
Primovist;
Hepatocyte-specific agent;
Liver cirrhosis;
Small hepatocellular carcinoma
- From:
Chinese Journal of Hepatobiliary Surgery
2013;19(12):955-960
- CountryChina
- Language:Chinese
-
Abstract:
Primovist is a newly developed hepatocytespecific agent that is transported into the hepatocyte through organic anion transporting polypeptides (OATPs) and excre ted into bile through canalicular multiorganic anion trans porters.Primovist uptake is usually reduced in HCC cells that present hypointensity on the hepatobiliary phase,there fore this agent may help differentiate HCC from other neoplasms and improve histological grading.This article will further explore the use of Primovist in liver cirrhosis and small hepatocellular carcinoma.