The clinical and imaging features of pulmonary metastasis of giant cell tumor of bone
10.3760/cma.j.issn.1005-1201.2013.12.012
- VernacularTitle:骨巨细胞瘤肺转移的临床和影像特征
- Author:
Dong YAN
;
Aihong YU
;
Baoyue LIU
;
Chen WANG
;
Yongbin SU
;
Xiaoguang CHENG
- Publication Type:Journal Article
- Keywords:
Giant cell tumor of bone;
Lung neoplasms;
Neoplasm metastasis;
Tomography,X-ray computed
- From:
Chinese Journal of Radiology
2013;47(12):1102-1104
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical and imaging features of pulmonary metastasis of giant cell tumor of bone for clinical diagnosis and treatment.Methods Five patients with histologically proven pulmonary metastasis from giant cell tumor of bone were reviewed,the imaging features and the progression of the pulmonary metastasis were evaluated.Results The first operation of primary tumor was curettages and then local recurrence was seen in all 5 cases.The interval to metastasis ranged from 5 to 26 months.Pulmonary metastasis was diagnosed by chest radiographs in 4 cases and CT in all 5 cases.The imaging findings included solitary solid nodule (n =1),multiple solid nodules and mass (n =5),multiple groundglass nodules (n =1) and complex form (n =2).The dynamic follow-up CT findings showed spontaneous regress nodules (n =1),metastasis occurring again 19 months after surgery of solitary nodule (n =1),some solid nodules unchangable for a long time in 3 patients with multiple nodules.Conclusions The dynamic follow-up CT findings of pulmonary metastasis of giant cell tumor of bone are specific.The regular follow-up could play an essential role in early detection and prognosis of pulmonary metastasis within 2 years after primary tumor diagnosed.